Support for UNRWA's survival

The United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) provides life-saving humanitarian aid for 5·4 million Palestine refugees now entering their eighth decade of statelessness and conflict. About a third of Palestine refugees still live in 58 recognised camps. UNRWA operates 702 schools and 144 health centres, some of which are affected by the ongoing humanitarian disasters in Syria and the Gaza Strip. It has dramatically reduced the prevalence of infectious diseases, mortality, and illiteracy. Its social services include rebuilding infrastructure and homes that have been destroyed by conflict and providing cash assistance and micro-finance loans for Palestinians whose rights are curtailed and who are denied the right of return to their homeland

Expression of the Arabidopsis thaliana BBX32 Gene in Soybean Increases Grain Yield

Crop yield is a highly complex quantitative trait. Historically, successful breeding for improved grain yield has led to crop plants with improved source capacity, altered plant architecture, and increased resistance to abiotic and biotic stresses. To date, transgenic approaches towards improving crop grain yield have primarily focused on protecting plants from herbicide, insects, or disease. In contrast, we have focused on identifying genes that, when expressed in soybean, improve the intrinsic ability of the plant to yield more. Through the large scale screening of candidate genes in transgenic soybean, we identified an Arabidopsis thaliana B-box domain gene (AtBBX32) that significantly increases soybean grain yield year after year in multiple transgenic events in multi-location field trials. In order to understand the underlying physiological changes that are associated with increased yield in transgenic soybean, we examined phenotypic differences in two AtBBX32-expressing lines and found increases in plant height and node, flower, pod, and seed number. We propose that these phenotypic changes are likely the result of changes in the timing of reproductive development in transgenic soybean that lead to the increased duration of the pod and seed development period. Consistent with the role of BBX32 in A. thaliana in regulating light signaling, we show that the constitutive expression of AtBBX32 in soybean alters the abundance of a subset of gene transcripts in the early morning hours. In particular, AtBBX32 alters transcript levels of the soybean clock genes GmTOC1 and LHY-CCA1-like2 (GmLCL2). We propose that through the expression of AtBBX32 and modulation of the abundance of circadian clock genes during the transition from dark to light, the timing of critical phases of reproductive development are altered. These findings demonstrate a specific role for AtBBX32 in modulating soybean development, and demonstrate the validity of expressing single genes in crops to deliver increased agricultural productivity

A Public Health Perspective on the Fukushima Nuclear Disaster

IN THIS ARTICLE I REVIEW KEY ASPECTS OF OUR KNOWLEDGE ABOUT ION- izing radiation and health, and I provide a public health perspective on priority measures to protect the people and environment affected by the Fukushima nuclear disaster. Because radioactive fallout spreads without regard to borders and affects people indiscriminately, any nuclear disaster that disperses radioactive materials in the air, soil, or water is of global concern. The public health aspects of the Fukushima disaster are therefore of global health significance. A disaster with uncontrolled radioactive release is possible at any nuclear plant. Ionizing Radiation and Human Health The Danger Ionizing radiation is intensely biologically injurious, not because it contains extraordinarily large amounts of energy but because that energy is bundled and delivered to cells in large packets. The energy of a diagnostic X-ray, for example, is typically around 15,000 times as large as the energy of a chemical bond. Larg

Australia's contribution to global immunisation

Abstract Objective : To review Australian contributions to global immunisation. Approach : We summarise Australian scientific and program contributions to vaccines and global immunisation, describe key developments and strengths in Australia's national immunisation program, and outline how both of these can link with Australia's increasing international development budget to build Australia's future contribution to global immunisation. Conclusions : Australian contributions to vaccines and immunisation have been substantial, and Australia offers a range of good practices in its domestic and development approaches. There are major opportunities to build on this strong track record. These include committing to help roll out important new life‐saving vaccines against pneumococcal disease, rotavirus and human papilloma virus (HPV) to the children who need them most, but whose communities can least afford them. Implications : Australia is one of a few countries expanding their aid budgets towards 0.7% development assistance and other development commitments. Given the importance of immunisation to health gains, Australia is well placed to expand its investment in immunisation within its development portfolio. The GAVI Alliance is the best‐established global mechanism to do this. Additionally, however, Australia could harness other national and regional mechanisms to support low and middle‐income countries, thereby complementing GAVI's focus and global needs

Kodiak brown bears surf the salmon red wave: direct evidence from GPS collared individuals

One of the goals of Ecosystems Base Fisheries Management (EBFM) is recognizing and mitigating indirect effects of fisheries on trophic interactions. Most research on indirect effects has considered how the abundance of managed fishes influences trophic interactions with other species. However, recent work has shown that attributes besides abundance, such as life history variation, can strongly mediate species interactions.  For example, phenological variation within prey species may enhance foraging opportunities for mobile predators by increasing the duration over which predators can target vulnerable life stages of prey.  Here, we present direct evidence of individual brown bears (Ursus arctos middendorffi) exploiting variation in sockeye salmon spawning phenology by tracking salmon runs across a 2,800 km2 region of Kodiak Island.  Data from 40 GPS collared brown bears show bears visited multiple spawning sites in synchrony with the order of spawning phenology.  The average time spent feeding on salmon was 67 days, while the average duration of spawning for one population was only 40 days.  The number of sites used was correlated with the number of days a bear exploited salmon, suggesting phenological variation in the study area influenced bear access to salmon, a resource which strongly influences bear fitness.  These results suggest fisheries managers attempting to maximize harvest while minimizing impacts on brown bears should strive to protect the population diversity that underlies the phenological variation used by wildlife consumers.  These results underscore the need to understand how fisheries affect life history diversity in addition to abundance in order to minimize negative effects of fisheries management on non-target species, a goal of EBFM